HoD and Associate Professor,
Department of Biotechnology
Chaithanya Madhurantakam is a structural biologist and a protein biochemist. He has a Doctoral degree in Biotechnology from the Department of Biotechnology, Indian Institute of Technology (IIT), Kharagpur, India. His research work focuses on structural characterization of proteins through X-ray crystallography. His research work over a period of 15 years include around 7 years of post- doctoral experience (Karolinska Institute, Stockholm; University of Zurich, Zurich and Vrije University, Brussels) covering 18 international peer-reviewed publications, 2 invited book chapters and 3 international publications in proceedings of conference.
Honors and AwardsRamalingaswamy Fellow (DBT, GoI)
Post Doctoral Fellow- Vrije University, VIB, Brussels, Belgium (2013-2014)
Post Doctoral Fellow - University of Zurich, Zurich, Switzerland (2010- 2013)
Post Doctoral Fellow - Karolinska Institute, Stockholm, Sweden (2008 to 2010)
UGC SRF- University Grants Commission (2007-2008)
UGC JRF- University Grants Commission (2005-2007)
Qualified GATE (2004) (Ranked 753)
Selected PublicationsStructures of designed armadillo repeat proteins binding to peptides fused to globular domains.
Hansen S, Kiefer JD, Madhurantakam C, Mittl PRE, Pluckthun A.
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
Reichen C, Hansen S, Forzani C, Honegger A, Fleishman SJ, Zhou T, Parmeggiani F, Ernst P, Madhurantakam C, Ewald C, Mittl PRE, Zerbe O, Baker D, Caflisch A, Pluckthun A.
J. Mol. Biol.,
Structure and Energetic Contributions of a Designed Modular Peptide-Binding Protein with Picomolar Affinity.
Hansen S, Tremmel D, Madhurantakam C, Reichen C, Mittl PR, Pluckthun A.
J Am Chem Soc. 2016 Mar 16;138(10):3526-32. doi: 10.1021/jacs.6b00099. Epub 2016 Mar 2.,
Structures of designed armadillo-repeat proteins show propagation of inter-repeat interface effects
Reichen C, Madhurantakam C, Hansen S, Grutter MG, Pluckthun A, Mittl PR.
Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):168-75. doi: 10.1107/S2059798315023116. Epub 2016 Jan 1. PMID: 26894544,
Crystal Structures of Designed Armadillo Repeat Proteins: Implications of Construct Design and Crystallization Conditions on Overall Structure
Reichen C, Madhurantakam C, Pluckthun A, Mittl PR.
Protein Sci. 2014 Aug 13. doi: 10.1002/pro.2535. [Epub ahead of print] PMID: 25132085,